SS-31
In stockElamipretideTetrapeptide D-Arg-Dmt-Lys-Phe-NH2, also called elamipretide, designed to target the inner mitochondrial membrane. Researchers study its binding to cardiolipin and its effects on electron transport in isolated mitochondria.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Longevity & Energy).
Research literature, not dosing or treatment instructions.
- Cell-permeable peptide antioxidants targeted to the inner mitochondrial membrane were tested on mitochondrial swelling, cytochrome c release and oxidative cell death. (PMID 15178689)
- SS-31 was studied for its interaction with cardiolipin and for ATP recovery in ischaemic mitochondria in a kidney model. (PMID 23813215)
- SS-31 was shown to bind cardiolipin and to affect the cytochrome c and cardiolipin complex, electron transport and ATP synthesis. (PMID 24134698)
- A review covers the discovery and development of peptides that target the inner mitochondrial membrane. (PMID 21638136)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about SS-31
How much published research is there on SS-31?
The research library's PubMed search for SS-31 returned 469 records on 5 October 2026, 96 of them reviews. The library lists 4 studies chosen for what they measured. ClinicalTrials.gov lists 21 registered studies naming SS-31, 19 of them sponsored by Stealth BioTherapeutics Inc. (checked 5 October 2026).
Is SS-31 an approved medicine?
Medicinal products containing SS-31 appear in Drugs@FDA, and the research material we supply is not one of them. Drugs@FDA lists 1 application naming this active ingredient, marketing status as listed: Prescription (checked 5 October 2026). Those are medicinal products. The research material we supply is not one of them. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
Is SS-31 the same as elamipretide?
Yes. The literature uses the names SS-31, elamipretide, MTP-131 and Bendavia for the tetrapeptide D-Arg-Dmt-Lys-Phe-NH2.
How is the identity of SS-31 confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 639.8 Da listed on this page. The research library's guide to reading a certificate explains each field.
What other names is SS-31 published under?
SS-31 is also written Elamipretide, MTP-131, Bendavia and SS 31. The catalog lists it under the name SS-31.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is SS-31?
SS-31, also called elamipretide, is the tetrapeptide D-Arg-Dmt-Lys-Phe-NH2, designed to target the inner mitochondrial membrane. Published work describes its interaction with cardiolipin and its effects on electron transport and ATP synthesis in isolated mitochondria and animal models. We supply SS-31 as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of SS-31?
SS-31 has the molecular formula C32H49N9O5, an average molecular weight of 639.8 Da and CAS number 736992-21-5.
Chemistry checked against PubChem (CID 11764719), 5 October 2026; full chemistry record in the research library.
What does published research on SS-31 cover?
A PubMed search for SS-31 returned 469 records on 5 October 2026, 96 of them reviews. Our research library lists 4 of these studies, chosen for what they measured.
- Cell-permeable peptide antioxidants targeted to the inner mitochondrial membrane were tested on mitochondrial swelling, cytochrome c release and oxidative cell death. (Zhao et al., J Biol Chem, 2004; PMID 15178689)
- SS-31 was studied for its interaction with cardiolipin and for ATP recovery in ischaemic mitochondria in a kidney model. (Birk et al., J Am Soc Nephrol, 2013; PMID 23813215)
- SS-31 was shown to bind cardiolipin and to affect the cytochrome c and cardiolipin complex, electron transport and ATP synthesis. (Birk et al., Br J Pharmacol, 2014; PMID 24134698)
- A review covers the discovery and development of peptides that target the inner mitochondrial membrane. (Szeto et al., Pharm Res, 2011; PMID 21638136)
Mechanism, every cited study and the regulator records are on the SS-31 page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is SS-31 supplied and stored?
SS-31 is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of SS-31?
Drugs@FDA lists 1 application naming this active ingredient, marketing status as listed: Prescription (checked 5 October 2026). Those are medicinal products. The research material we supply is not one of them.
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- SS-31: chemistry, literature and regulatory status
- Mitochondria-linked peptides
- How to read a certificate of analysis
Related compounds in the catalog: