KPV
Coming soonα-MSH (11-13)Tripeptide Lys-Pro-Val, the C-terminal fragment (residues 11 to 13) of alpha-MSH. Researchers study it in mouse and cell-culture inflammation models and for its uptake through the PepT1 peptide transporter.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Recovery & Repair).
Research literature, not dosing or treatment instructions.
- In a mouse model of crystal-induced peritonitis KPV was compared with alpha-MSH, a core melanocortin peptide and a melanocortin receptor 3 and 4 agonist. (PMID 12750433)
- In murine models of inflammatory bowel disease KPV was tested for its effect on inflammatory readouts. (PMID 18092346)
- One study examined whether KPV activity depends on the PepT1 di- and tripeptide transporter in intestinal epithelial and immune cells and in mouse colitis. (PMID 18061177)
- In cultured cells an immobilised alpha-MSH 10 to 13 peptide was examined for its effect on TNF-alpha stimulated NF-kB activation and for the receptor and cyclic AMP dependence of that signalling. (PMID 16274845)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about KPV
How much published research is there on KPV?
The research library's PubMed search for KPV returned 39 records on 5 October 2026, 7 of them reviews. The library lists 5 studies chosen for what they measured. ClinicalTrials.gov lists no registered study naming KPV (checked 5 October 2026).
Is KPV an approved medicine?
No medicinal product containing KPV is listed in Drugs@FDA (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
How is KPV related to alpha-MSH?
KPV is the C-terminal tripeptide (residues 11 to 13) of alpha-melanocyte-stimulating hormone. In a mouse model of crystal-induced peritonitis it was compared with the full hormone (PMID 12750433).
How is the identity of KPV confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 342.4 Da listed on this page. The research library's guide to reading a certificate explains each field.
What other names is KPV published under?
KPV is also written α-MSH (11-13) and KPV peptide. The catalog lists it under the name KPV.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is KPV?
KPV is the tripeptide Lys-Pro-Val, the C-terminal fragment (residues 11 to 13) of alpha-melanocyte-stimulating hormone. Mouse and cell-culture studies examine it in inflammation models and report that its uptake involves the PepT1 peptide transporter. We supply KPV as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of KPV?
KPV has the molecular formula C16H30N4O4, an average molecular weight of 342.4 Da and CAS number 67727-97-3.
Chemistry checked against PubChem (CID 125672), 5 October 2026; full chemistry record in the research library.
What does published research on KPV cover?
A PubMed search for KPV returned 39 records on 5 October 2026, 7 of them reviews. Our research library lists 5 of these studies, chosen for what they measured.
- In a mouse model of crystal-induced peritonitis KPV was compared with alpha-MSH, a core melanocortin peptide and a melanocortin receptor 3 and 4 agonist. (Getting et al., J Pharmacol Exp Ther, 2003; PMID 12750433)
- In murine models of inflammatory bowel disease KPV was tested for its effect on inflammatory readouts. (Kannengiesser et al., Inflamm Bowel Dis, 2008; PMID 18092346)
- One study examined whether KPV activity depends on the PepT1 di- and tripeptide transporter in intestinal epithelial and immune cells and in mouse colitis. (Dalmasso et al., Gastroenterology, 2008; PMID 18061177)
- In cultured cells an immobilised alpha-MSH 10 to 13 peptide was examined for its effect on TNF-alpha stimulated NF-kB activation and for the receptor and cyclic AMP dependence of that signalling. (Kelly et al., Peptides, 2006; PMID 16274845)
Mechanism, every cited study and the regulator records are on the KPV page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is KPV supplied and stored?
KPV is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of KPV?
Drugs@FDA lists no application naming KPV as an active ingredient (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- KPV: chemistry, literature and regulatory status
- Melanocortin receptors
- How to read a certificate of analysis
Related compounds in the catalog: