Kisspeptin-10
In stockMetastin (45-54)C-terminal decapeptide of the kisspeptins, the natural ligands of the receptor GPR54. Researchers study receptor discovery, signalling and receptor genetics.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Hormone & Libido).
Research literature, not dosing or treatment instructions.
- Kisspeptins of 54, 14 and 13 amino acids were isolated from human placenta as natural agonists of the orphan receptor GPR54, with a common RF-amide C terminus. (PMID 11457843)
- The KiSS-1 gene product was identified as the peptide ligand of the orphan receptor, and a human receptor (AXOR12) was cloned and shown to be activated by KiSS-1 derived peptides. (PMID 11385580, PMID 11387329)
- A genetic study in a human family and in mice linked GPR54 to the onset of puberty. (PMID 14573733)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about Kisspeptin-10
How much published research is there on Kisspeptin-10?
The research library's PubMed search for Kisspeptin-10 returned 333 records on 5 October 2026, 14 of them reviews. The library lists 4 studies chosen for what they measured. ClinicalTrials.gov lists 5 registered studies naming Kisspeptin-10 (checked 5 October 2026).
Is Kisspeptin-10 an approved medicine?
No centrally authorised medicine containing Kisspeptin-10 is listed in the EMA medicines database (checked 5 October 2026), and the research material we supply is not a medicine. The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming Kisspeptin-10 (searched as kisspeptin) as an active substance. National authorisations are not in that dataset. The WADA 2026 list names kisspeptin and its agonist analogues under S2.2.1. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
Which part of the kisspeptins is Kisspeptin-10?
The C-terminal decapeptide, residues 45 to 54, of the kisspeptins. Kisspeptins of 54, 14 and 13 amino acids were isolated from human placenta as natural agonists of the receptor GPR54 (PMID 11457843).
How is the identity of Kisspeptin-10 confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 1302.4 Da listed on this page. The research library's guide to reading a certificate explains each field.
What other names is Kisspeptin-10 published under?
Kisspeptin-10 is also written Metastin (45-54) and Kisspeptin 10. The catalog lists it under the name Kisspeptin-10.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is Kisspeptin-10?
Kisspeptin-10 is the C-terminal decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 of the kisspeptins, the endogenous ligands of the G-protein-coupled receptor GPR54. Published work covers receptor discovery and receptor genetics. We supply Kisspeptin-10 as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of Kisspeptin-10?
Kisspeptin-10 has the molecular formula C63H83N17O14, an average molecular weight of 1302.4 Da and CAS number 374675-21-5.
Chemistry checked against PubChem (CID 25240297), 5 October 2026; full chemistry record in the research library.
What does published research on Kisspeptin-10 cover?
A PubMed search for Kisspeptin-10 returned 333 records on 5 October 2026, 14 of them reviews. Our research library lists 4 of these studies, chosen for what they measured.
- Kisspeptins of 54, 14 and 13 amino acids were isolated from human placenta as natural agonists of the orphan receptor GPR54, with a common RF-amide C terminus. (Kotani et al., J Biol Chem, 2001; PMID 11457843)
- The KiSS-1 gene product was identified as the peptide ligand of the orphan receptor, and a human receptor (AXOR12) was cloned and shown to be activated by KiSS-1 derived peptides. (Ohtaki et al., Nature, 2001; PMID 11385580; Muir et al., J Biol Chem, 2001; PMID 11387329)
- A genetic study in a human family and in mice linked GPR54 to the onset of puberty. (Seminara et al., N Engl J Med, 2003; PMID 14573733)
Mechanism, every cited study and the regulator records are on the Kisspeptin-10 page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is Kisspeptin-10 supplied and stored?
Kisspeptin-10 is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of Kisspeptin-10?
The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming Kisspeptin-10 (searched as kisspeptin) as an active substance. National authorisations are not in that dataset.
The exact name appears in 5 MHRA Products documents as text only, not as an active substance (checked 5 October 2026).
The WADA 2026 Prohibited List names this substance under S2.2.1. A WADA entry is a sporting rule, not a statement about legality outside sport.
The WADA 2026 list names kisspeptin and its agonist analogues under S2.2.1.
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.