DSIP
Coming soonDelta sleep-inducing peptideDelta sleep-inducing peptide, the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, isolated in 1977 from rabbit cerebral venous blood. Its mechanism is still incompletely characterised.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Cognition & Focus).
Research literature, not dosing or treatment instructions.
- The original paper isolated the peptide from rabbit cerebral venous blood, determined its sequence and tested the peptide and analogues for effects on EEG activity in rabbits. (PMID 265572, PMID 568769)
- A 1986 review updates the literature on sleep and other effects in animals and humans. (PMID 3550726)
- Degradation and aggregation of DSIP and two analogues were measured in human and rat blood plasma and serum. (PMID 3628078)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about DSIP
How much published research is there on DSIP?
The research library's PubMed search for DSIP returned 462 records on 5 October 2026, 24 of them reviews. The library lists 4 studies chosen for what they measured. ClinicalTrials.gov lists no registered study naming DSIP (checked 5 October 2026).
Is DSIP an approved medicine?
No centrally authorised medicine containing DSIP is listed in the EMA medicines database (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
Why is the literature on DSIP so old?
The foundational papers date from 1977 and the 1980s, and the mechanism remains incompletely characterised. The research library lists the original isolation paper and a 1986 review (PMIDs 265572 and 3550726).
How is the identity of DSIP confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 848.8 Da listed on this page. The research library's guide to reading a certificate explains each field.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
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For research use only. Not for human or veterinary use.
What is DSIP?
DSIP, delta sleep-inducing peptide, is the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, isolated in 1977 from the cerebral venous blood of rabbits. Its mechanism remains incompletely characterised, and the foundational literature dates from the 1970s and 1980s. We supply DSIP as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of DSIP?
DSIP has the molecular formula C35H48N10O15, an average molecular weight of 848.8 Da and CAS number 62568-57-4.
Chemistry checked against PubChem (CID 68816), 5 October 2026; full chemistry record in the research library.
What does published research on DSIP cover?
A PubMed search for DSIP returned 462 records on 5 October 2026, 24 of them reviews. Our research library lists 4 of these studies, chosen for what they measured.
- The original paper isolated the peptide from rabbit cerebral venous blood, determined its sequence and tested the peptide and analogues for effects on EEG activity in rabbits. (Schoenenberger et al., Proc Natl Acad Sci U S A, 1977; PMID 265572; Schoenenberger et al., Pflugers Arch, 1978; PMID 568769)
- A 1986 review updates the literature on sleep and other effects in animals and humans. (Graf et al., Peptides, 1986; PMID 3550726)
- Degradation and aggregation of DSIP and two analogues were measured in human and rat blood plasma and serum. (Graf et al., Peptides, 1987; PMID 3628078)
Mechanism, every cited study and the regulator records are on the DSIP page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is DSIP supplied and stored?
DSIP is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of DSIP?
The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming DSIP as an active substance. National authorisations are not in that dataset.
No SmPC, PIL or PAR document in MHRA Products matches the exact name (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
Related compounds in the catalog: